Going Off Tafinlar and Mekinist again!

19 04 2016

Another update on the side effects of Tafinlar and Mekinist.  Well here we go again, or not!  I had restarted the chemo Tafinlar and Mekinist and was hopeful I would continue on the medication without side effects.  After a month back on it I was feeling very lucky that I was doing so well.  Month two was just about the same, doing much better that expected until I woke up one morning with just about every side effect listed for both medication.  Off the chemo again with hopes that in a week or 10 days I would be well enough to restart it.  Well this time it’s not looking so good.  I had initially woke up with fever, chills, severe stomach pains that felt like I had swallowed a bucket of razor blades, migraines, vomiting, diarrhea, and overall fatigue and feeling like poop.  I went off the chemo and about 4 days later the stomach pain, vomiting and diarrhea subsided.  Whew, I was so glad that was over but I still had a low-grade fever and migraine for the next few days.  Then the worst ever, I started having swelling in both feet and ankles with severe sharp burning pain that could not be controlled by anything.  I thought this was strange and hopeful it would get better.  No such luck its only getting worse each day.  At first there was no discoloration in the skin just pain and swelling.  I was thinking it was probably joint pain, arthritis or some sort of muscle pain, all noted in the list of side effects.  Things changed over the weekend and have gradually gotten worse.  There is now severe edema in both feet and ankles and the swelling and pain is moving up my leg and into my knee on my left leg.  I am almost positive I have developed blood clots in both feet and ankles, also on the list of side effects.  Yes I know the risks of blood clots.  I am planning on going into my physicians office or to the ED tomorrow or Wednesday depending on what my physician thinks.  When I put any pressure on my right foot it feels like all the bones in my foot and ankle have been crushed and I am trying to walk on crushed bones.  The right foot is the same but the heel is a little more painful on this foot but it dies not radiate up the leg into the knee like the left.  Wow,  I never thought anything could be this painful and bring tears to my eyes so quickly.  I also feel like the two overstuffed sausages attached to the end of each leg are the most disgusting foreign objects I have ever seen.  I want to know where my feet went and I want them back.

I want to say again as I have said so many times that I am very lucky and thankful to have such wonderful physicians.  I am thankful to Dave for leading me to the right physicians for treatment.  I am hopeful that once again I will be in good hands and on the road to recovery soon.

I am also so very thankful for all the support and prayers that have been a constant in this crazy cancer experience.  I will be forever grateful to all of you who give me reasons to fight and who bring a smile to my face when I think of you.  I truly have been blessed with so many wonderful people in my life.  God bless you all.





10 responses

19 04 2016
Susan Reichling

Praying for relief for you, Patty. Thank you for sharing your journey. It can’t be easy! If there is anything I can do for you, please call or text. God bless you with His healing, peace, and comfort. Amens

19 04 2016
Linda Birks

I am sending up prayers for you Patty.

19 04 2016

Lord God we don’t understand all we experience on Earth. Your word says our time here is just a moment and then eternity in paradise with you. You direct our path. You have given Patty wonderful doctors and family and friends. She is rich beyond all human understanding. Please I beg you Lord help Patty in the time of her need. Quiet the pain. Clear her mind of migraines. Let her blood flow smoothly and the swelling ease. Bless her for her honesty, her patience, her diligence. Right now Lird give her comfort and peace. Provide a sign of hope that she will recognize. Continue to pour out love on, over and around Patty and her family.

19 04 2016

Sending lots of love and prayers. Love you to the moon and back. I pray for you everyday. Love you. Keep up that fight girl. You will do great.❤️❤️❤️❤️

19 04 2016
Shelly Harrod

Praying for you. God is never blind to your tears, never deaf to your prayers, and He is never silent to your pain. All things are possible with Him.

19 04 2016
Mary Jo Wasser

Patty, I am with you in spirit and prayer–always! Peace and all Good! Mary Jo

19 04 2016
Gail Clodfelter

Prayers for comfort and healing for you Patty!

26 04 2016
Barb Ratliff

I just realized a couple of nights ago that you have this blog and I’ve been reading it ever since. Please know that I think of you often and have been praying for you regularly ever since we left Springfield.
Your blog has been SO inspirational. In one post, you questioned why you were chosen to endure this cancer experience. Well I believe you were chosen because of your inspiration and your ability to teach others how to treasure what is most important in life. You have most certainly done this for me and it will be passed on to my children and hopefully for generations to come. You have single-handedly redirected my family’s future.
We love you; we love Trentin.
God bless you.

28 04 2016
Patty Knight

Thank you so much Barb
You have no idea how much your words touched me. I miss you and your family so much and pray you are all doing well and that Zane is still amazing others with his talent on the ice. Love ya

4 06 2017
Patty Knight

Thank you Barb for the kind words. We miss you here in Springfield. Love you

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